Website is intended for physicians
Search:
Всего найдено: 2

 

Abstract

Recently, there has been a steady tendency to expand indications for organpreserving operations for kidney tumors.The success of the operation depends on many factors and, first of all, on the completeness of tumor removal and reliability of hemostasis without damage to the blood supply of the entire organ with a minimum time of thermal or cold ischemia. Particularly difficult for surgeon are tumors with intrarenal arrangement. This is due to difficulties of intraoperative determination of tumor localization, as well as technical aspects of removal of big newgrowth with the implementation of adequate hemostasis in the bed of the removed tumor. If resection of kidney poles with a tumor is a fairly simple operation, the enucleation of the latter in the depth of the parenchyma at the location in the middle segments of the kidney and in direct contact with large vessels, is of great technical complexity As a rule, central location of intrarenal tumor requires the "exposure" of kidney parenchyma by a separate incision, up to the sectional. The surgeon's task is to minimize such transparenchymal access, which creates difficulties with hemostasis in a limited space and time limit of thermal ischemia. Hemostatic insufficiency, in turn, can lead to postoperative bleeding, and formation of arteriovenous fistulas. Superselective embolization of branches of the renal artery supplying the intrarenal tumor ensures the subsequent optimal revision of the bed of the removed tumor, minimizes blood loss and allows to refuses blood flow arrest of entire organ.

Case report: article presents data of a young 33-year-old patient with a congenital anomaly in the blood supply of left kidney in the form of a multiple renal artery and kidney tumor T1AN0M0. Ultrasound, CT and MRI revealed an intraparenchymal tumor of the left kidney measuring 2,3x2,5x2,2 cm, with blood supply by 4 arteries extending from the aorta. As the first stage, superselective embolization of tumor's blood supplying artery with PVA 355-500 microns was performed. The second stage was the enucleation of a tumor of left kidney under the control of intraoperative ultrasound without thermal kidney ischemia. Intraoperative blood loss less than 150 ml. The patient was discharged on the 7th day

Conclusion: performing selective embolization of the renal artery feeding the tumor makes it possible to perform the operation without thermal ischemia of the kidney with minimal blood loss.

  

References

1.      Alyaev YU.G., Glybochko P.V., Grigoryan Z.G., Gazimiev M.A. Organ-preserving surgery for kidney tumors. M.:GEOTAR-Media,2009; S. 55-64. [In Russ.]

2.      3-D - technology for operations on the kidney: from virtual to real surgery. Pod red. Glybochko P.V., Alyaeva YU.G. M.: GEOTAR-Media, 2014; S.91-92. [In Russ.]

3.      MacLeman S, Imamura M., Lapitan M.C. Systematic review of perioperative end quality-of-life outcomes following surgical management of localized renal cancer. Eur Urol, 2012; 62:1097.

4.      May M., Brookman-Amissah S, Pflanz S., Roigas J., Hoschke B., Kendel F. Pre-operative renal arterial embolisation does not provide survival benefit in patients with radical nephrectomy for renal cell carcinoma. Br J Radiol, 2009; 82:724.

5.      Maxwell N.J., Saleem Amer N, Rogers E. Kiely D, Sweeney P, Brady AP, Renal artery embolisation in the palliative treatment of renal carcinoma. Br J Radiol, 2007; 80:96.

6.      Vishnyakova M.V., Vashchenko A.V., Demidov I.N., Gegenava B.B., Denisova L.B. Endovascular treatment of vascular pathology using three-dimensional navigation. First experience. Rossijskij elektronnyj zhurnal luchevoj diagnostiki. 2011; T1. №3. S.44-53. [In Russ.]

7.      Gegenava B.B., Vishnyakova M.V., Kiselev A.M., Vashchenko A.V., Demidov I.N., Vishnyakova M.V. (ml.) Endovascular treatment of arteriovenous malformations of cerebral vessels using three-dimensional guidance technology. Al'manah klinicheskoj mediciny. 2013g., №29 str.3-7. [In Russ.]

8.      Kokov L.S., Storozhev R.V., Bocharov S.M., Anisimov YU.A., Belozerov G.E., Pinchuk A.V., Experience in embolization of the artery of a renal allograft before nephrotransplantectomy at a long time after surgery. Transplantologiya. 2012; № 1-2. S. 70-73. [In Russ.]

9.      Bazaev V.V., Gegenava B.B., Stashuk G.A., Bychkova N.V., Kazanceva I.A. Successful resection of the kidney in a patient with rupture of angiomyolipoma with preliminary superselective embolization of renal vessels. Annaly hirurgii, 2018; T.23 №4. S239-246. [In Russ.]

Abstract:

Radiofrequency (RF) ablation is a minimally invasive method. Application of RF ablation allowed to expand indications for more radical treatment of kidney tumors in patients, whom traditional nephrectomy or kidney resection are impossible, due to extremely adverse somatic status

Efficiency and safety of RF ablation are significantly increased if preceded in combination with superselective occlusion of blood vessels, supplying the tumor. We possess the experience of application of superselective embolization in combination with RF ablation of two patients with kidney tumors. In both cases a good result of combined treatment has been observed.

This combination (superselective embolization + RF ablation) can be an alternative to open operation on kidney in number of patients, expanding the arsenal of modern minimally invasive kidney tumor's treatment methods. 

 

Reference 

1.    Pavlov AJu., Klimenko A. A., Momdzhan B.K., Ivanov S.A. Radiochastotnaja intersticial'naja termoabljacija (RChA) raka pochki. [Radiofrequency interstitial termal ablation of renal cancer]. Jeksperimental'naja i klinicheskaja urologija. 2011; 2(3): 112-113 [In Russ].

2.    European Network of Cancer Registries. Eurocim version 4.0. European incidence database V2.3, 730 entity dictionary (2001). Lyon, 2001.

3.    Zlokachestvennye novoobrazovanija v Rossii v 2008 g. (zabolevaemost' i smertnost'). [Malignant neoplasms in Russian Federation in 2008 (morbidity and mortality)]. Pod red. V.I. Chissova, V.V. Starinskogo, G.V. Petrovoj. M. FGU «MNIOI im. P.A. Gercena Rosmedtehnologij». 2010 [ In Russ].

4.    Chow W.H., Devesa S.S., Warren J.L., Freumeni J.FJr. Rising incidence of renal cell carcer in the United States. JAMA. 1999; 281:1628-31.

5.    Nguyen M.M., ill I.S., Ellison L.M. The evolving presentation of renal carcinoma in the United States: trends from the Surveillance, Epidemiology, and End Results program. J. Urol. 2006; 176: 2397-400; discussion 2400.

6.    Kummerlin I.P., ten Kate F.J., Wijkstra H., de la Rosette J.J., Laguna M.P. Changes in the stage and surgical management of renal tumours during 1995-2005: an analysis of the Dutch national histopathology registry. BJU Int. 2008; 102 (8): 946-51. Epub 2008 Jun 28.

7.    Ankem M.K., Nakada S.Y. Needle-nephron-sparing surgery. BJU Int. 2005; 95 (2): 46-51.

8.    Havranek E., Anderson C. Future prospects for nephron conservation in renal cell carcinoma. In: Kirby R.S., O’Leary M.P., editors. Hot topics in urology. Amsterdam. The Netherlands: Elsevier. 2004; 227-38.

9.    Marberger M., Mauerman J. Energy ablation nephron-sparing treatment of renal tumors. AUA Update Series. 2004; 23:178-83.

10.  Reddan D.N., Raj G.V., Polascik TJ. Management of small renal tumors: an overview. Am. J. Med. 2001; 110: 558-62.

11.  Weld K.J., Landman L. Comparison of cryoablation, radiofrequency ablation and high-intensity focused ultrasound for treating small renal tumors. BJU Int. 2005; 96:1224-9.

12.  Uzzo R.G., Novick A.C. Nephron sparing surgery for renal tumors: indications techniques and outcomes. J. Urol. 2001; 166:6-18.

13.  Dolgushin B.I., Kosyrev VJu., Ramprabanant S. Radiochastotnaja ablacija v onkologii. Prakticheskaja onkologija. 2007; 8(4): 219-227 [In Russ].

14.  Vogl TJ., Helmberger T.K., Mack M.G., Reiser M.F. (Eds.) Percutaneous Tumor Ablation in Medical Radiology. ISBN 978-3-540-22518-8 Springer. Berlin. Heidelberg. New York. 2008.

15.  Winthrop H. Hal, John P. McGahan, Daniel P. Link and Ralph W. deVere White. Combined Embolization and Percutaneous Radiofrequency Ablation of a Solid Renal Tumor. AJR. 2000; 174:1592-1594.

16.  Yamakado K., Nakatsuka A., Kobayashi S., Akeboshi M., Takaki H., Kariya Z., Kinbara H., Arima K., Yanagawa M., Hori Y., Kato H., Sugimura Y., Takeda K. Radiofrequency ablation combined with renal arterial embolization for the treatment of unresectable renal cell carcinoma larger than 3.5 cm: initial experience. Cardiovasc. Intervent. Radiol. 2006; 29(3): 389-94.

17.  Klingler H.C., Marberger M., Mauermann J. et al. ’Skipping’ is still a problem with radiofrequency ablation of small renal tumours. BJU Int. 2007; 99: 998-1001.

18.  Goldberg S.N., Gazelle G.S., Mueller P.R. Thermal ablation therapy for focal malignancy: A unified approach to underlying principles, techniques and diagnostic imaging guidance. Am. J. Roentgenol. 2000; 174: 323-31.

19.  Lee M. Ellis, Steven A. Curley, Kenneth K. Tanabe. Radiofrequency Ablation for Cancer.Current Indications, Techniques, and Outcomes. 2004; Springer-Verlag New York, Inc.

20.  Salagierski M., Salagierski M. Radiofrequency ablation partial nephrectomy: a new method of nephron-sparing surgery in selected patients. Int. J. Urol. 2006; 13(11): 1456-9.

21.  Veltri A., Garetto I., Pagano E., Tosetti I., Sacchetto P., Fava C. Percutaneous RF termal ablation of renal tumors: is US guidance really less favorable than other imaging guidance techniques? Cardiovasc. Intervent. Radiol. 2009; 32(1): 76-85. Epub 2008 Aug 15.

22.  Schirmang T.C., Mayo-Smith W.W., Dupuy D.E., Beland M.D., Grand D.J. Kidney neoplasms: renal halo sign after percutaneous radiofrequency ablation-incidence and clinical importance in 101 consecutive patients. Radiology. 2009; 253(1): 263-9. Epub 2009 Jul. 31.

ANGIOLOGIA.ru (АНГИОЛОГИЯ.ру) - портал о диагностике и лечении заболеваний сосудистой системы